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205 Recently, researchers have found a non-classical pathway of pyroptosis mediated by caspase-3 and gasdermin E (GSDME) in human primary cells and tumor cells

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We verified that 3-PLG-dopa-A-GSH not only had a significantly higher penetration across the BBB model than the non-targeted 3-PLG-dopa, but it also entered into healthy and PD midbrain organoids (Figs

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